The selective 5-HT<sub>2A</sub> receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [<sup>3</sup>H]25CN-NBOH.-论文-万方医学网

作者： Anders A,Jensen ^[1] ; Adam L,Halberstadt ^[2] ; Emil,Märcher-Rørsted ^[3] ; Anna U,Odland ^[3] ; Muhammad,Chatha ^[4] ; Nikolaj,Speth ^[5] ; Gudrun,Liebscher ^[3] ; Martin,Hansen ^[3] ; Hans,Bräuner-Osborne ^[3] ; Mikael,Palner ^[6] ; Jesper T,Andreasen ^[3] ; Jesper L,Kristensen ^[3]

作者单位： Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen Ø, Denmark. Electronic address: aaj@sund.ku.dk. ^[1] Department of Psychiatry, University of California San Diego, La Jolla, CA, United States; Research Service, VA San Diego Healthcare System, La Jolla, CA, United States. ^[2] Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen Ø, Denmark. ^[3] Department of Psychiatry, University of California San Diego, La Jolla, CA, United States. ^[4] Neurobiology Research Unit, Copenhagen University Hospital, Copenhagen, Denmark. ^[5] Neurobiology Research Unit, Copenhagen University Hospital, Copenhagen, Denmark; Center for Translational Neuromedicine, University of Copenhagen, Copenhagen, Denmark. ^[6]

主题词动物(Animals);苯呋喃类(Benzofurans);苄胺类(Benzylamines);结合部位(Binding Sites);小脑(Cerebellum);大脑皮质(Cerebral Cortex);脉络丛(Choroid Plexus);女(雌)性(Female);HEK293细胞(HEK293 Cells);致幻药(Hallucinogens);人类(Humans);动力学(Kinetics);移动(Locomotion);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);腈类(Nitriles);蛋白质结合(Protein Binding);大鼠(Rats);大鼠, Long-Evans(Rats, Long-Evans);受体, 血清素, 5-HT2A(Receptor, Serotonin, 5-HT2A);血清素5-HT2受体激动剂(Serotonin 5-HT2 Receptor Agonists);构效关系(Structure-Activity Relationship)

DOI 10.1016/j.bcp.2020.113979

PMID 32298690

发布时间 2020-12-01

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The selective 5-HT<sub>2A</sub> receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [<sup>3</sup>H]25CN-NBOH.

Biochemical pharmacology

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Biochemical pharmacology

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The selective 5-HT<sub>2A</sub> receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [<sup>3</sup>H]25CN-NBOH.

Biochemical pharmacology

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Biochemical pharmacology

相关期刊

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