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首页> Clinical cancer research : an official journal of the American Association for Cancer Research> Safety and Tolerability of Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGFβ and PD-L1, in Asian Patients with Pretreated Recurrent or Refractory Gastric Cancer.

Safety and Tolerability of Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGFβ and PD-L1, in Asian Patients with Pretreated Recurrent or Refractory Gastric Cancer.

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作者： Yoon-Koo,Kang ^[1] ; Yung-Jue,Bang ^[2] ; Shunsuke,Kondo ^[3] ; Hyun Cheol,Chung ^[4] ; Kei,Muro ^[5] ; Isabelle,Dussault ^[6] ; Christoph,Helwig ^[7] ; Motonobu,Osada ^[8] ; Toshihiko,Doi ^[9]

作者单位： Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. ^[1] Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea. bangyj@snu.ac.kr. ^[2] Department of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan. ^[3] Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, Japan. ^[4] Medical Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea. ^[5] Aichi Cancer Center Hospital, Nagoya, Japan. ^[6] EMD Serono Research & Development Institute, Inc., Billerica, Massachusetts; a business of Merck KGaA, Darmstadt, Germany. ^[7] Merck KGaA, Darmstadt, Germany. ^[8] Merck Biopharma, Tokyo, Japan; an affiliate of Merck KGaA, Darmstadt, Germany. ^[9] National Cancer Center Hospital East, Chiba, Japan. ^[10]

主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);抗药性, 肿瘤(Drug Resistance, Neoplasm);女(雌)性(Female);人类(Humans);男(雄)性(Male);中年人(Middle Aged);预后(Prognosis);复发(Recurrence);再治疗(Retreatment);胃肿瘤(Stomach Neoplasms);转化生长因子β(Transforming Growth Factor beta);治疗结果(Treatment Outcome)

DOI 10.1158/1078-0432.CCR-19-3806

PMID 32299818

发布时间 2021-09-14

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Clinical cancer research : an official journal of the American Association for Cancer Research

Clinical cancer research

2020年26卷13期

3202-3210页

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