Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome-Wide Association Study and Inverse Variance-Weighted Meta-Analysis.

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第一作者： Vivian K,Kawai

第一单位： Vanderbilt University Medical Center, Nashville, Tennessee.

作者： Vivian K,Kawai ^[1] ; Mingjian,Shi ^[2] ; Qiping,Feng ^[1] ; Cecilia P,Chung ^[3] ; Ge,Liu ^[1] ; Nancy J,Cox ^[4] ; Gail P,Jarvik ^[5] ; Ming T M,Lee ^[6] ; Scott J,Hebbring ^[7] ; John B,Harley ^[8] ; Kenneth M,Kaufman ^[8] ; Bahram,Namjou ^[9] ; Eric,Larson ^[10] ; Adam S,Gordon ^[11] ; Dan M,Roden ^[4] ; C Michael,Stein ^[1] ; Jonathan D,Mosley ^[4] ; eMERGE Investigators

作者单位： Vanderbilt University Medical Center, Nashville, Tennessee. ^[1] Vanderbilt University School of Medicine, Nashville, Tennessee. ^[2] Vanderbilt University Medical Center, Tennessee Valley Healthcare System Nashville Campus, and Vanderbilt University School of Medicine, Nashville, Tennessee. ^[3] Vanderbilt University Medical Center and Vanderbilt University School of Medicine, Nashville, Tennessee. ^[4] University of Washington, Seattle. ^[5] Geisinger, Danville, Pennsylvania. ^[6] Marshfield Clinic Health System, Marshfield, Wisconsin. ^[7] Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, and Cincinnati VA Medical Center, Cincinnati, Ohio. ^[8] Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio. ^[9] Kaiser Permanente Washington Health Research Institute, Seattle. ^[10] Northwestern University Feinberg School of Medicine, Chicago, Illinois. ^[11]

主题词关节炎, 类风湿(Arthritis, Rheumatoid);自身免疫疾病(Autoimmune Diseases);心血管疾病(Cardiovascular Diseases);糖尿病, 1型(Diabetes Mellitus, Type 1);糖尿病, 2型(Diabetes Mellitus, Type 2);基因多效性(Genetic Pleiotropy);疾病遗传易感性(Genetic Predisposition to Disease);人类(Humans);高脂血症(Hyperlipidemias);孟德尔随机化分析(Mendelian Randomization Analysis);多发性硬化(Multiple Sclerosis);肥胖症(Obesity);表型(Phenotype);肾功能不全, 慢性(Renal Insufficiency, Chronic);硬皮病, 系统性(Scleroderma, Systemic);统计学(主题)(Statistics as Topic);甲状腺炎, 自身免疫性(Thyroiditis, Autoimmune)

DOI 10.1002/art.41291

PMID 32307929

发布时间 2022-10-05

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Arthritis & rheumatology (Hoboken, N.J.)

2020年72卷9期

1483-1492页

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Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome-Wide Association Study and Inverse Variance-Weighted Meta-Analysis.

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Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome-Wide Association Study and Inverse Variance-Weighted Meta-Analysis.

Arthritis & rheumatology (Hoboken, N.J.)

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Arthritis & rheumatology (Hoboken, N.J.)

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