Expression of the nucleoside transporters hENT1 (SLC29) and hCNT1 (SLC28) in pediatric acute myeloid leukemia.

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作者： Adrian Christopher,Jaramillo ^[1] ; Isabelle,Hubeek ^[2] ; Richard,Broekhuizen ^[1] ; Marçal,Pastor-Anglada ^[3] ; Gertjan J L,Kaspers ^[4] ; Gerrit,Jansen ^[5] ; Jacqueline,Cloos ^[6] ; Godefridus J,Peters ^[7]

作者单位： Depts of Pediatric Hematology, Amsterdam University Medical Centers, Location VUMC, Amsterdam, The Netherlands. ^[1] Clinical Chemistry, Amsterdam University Medical Centers, Location VUMC, Amsterdam, The Netherlands. ^[2] Department of Hematology-Oncology, Pontifical Catholic University of Chile, Santiago, Chile. ^[3] Department de Bioquímica i Biologia Molecular, Universitat de Barcelona, Barcelona, Spain. ^[4] Princess Maxima Center for Pediatric Cancer, Utrecht, and SKION, The Netherlands. ^[5] Emma's Children's Hospital, Amsterdam UMC, Location VUMC, Pediatric Oncology, Amsterdam, The Netherlands. ^[6] Reumatology, Amsterdam University Medical Centers, Location VUMC, Amsterdam, The Netherlands. ^[7] Laboratory Medical Oncology, Amsterdam University Medical Centers, Location VUMC, Amsterdam, The Netherlands. ^[8] Department of Biochemistry, Medical University of Gdansk, Gdansk, Poland. ^[9]

关键词 Acute myeloid leukemia (AML)acute lymphoblastic leukemia (ALL)bovine serum albumin (BSA)cytarabine (Ara-C)deoxynucleoside analogs (NAs)human concentrative nucleoside transporter-1 (hCNT1)human equilibrative nucleoside transporter-1 (hENT1)phosphate buffered saline (PBS)