第一单位:
Stowers Institute for Medical Research, Kansas City, MO, USA.
作者:
John M,Perry [1]
;
Fang,Tao [2]
;
Anuradha,Roy [3]
;
Tara,Lin [4]
;
Xi C,He [1]
;
Shiyuan,Chen [2]
;
Xiuling,Lu [5]
;
Jacqelyn,Nemechek [3]
;
Linhao,Ruan [1]
;
Xiazhen,Yu [1]
;
Debra,Dukes [6]
;
Andrea,Moran [2]
;
Jennifer,Pace [1]
;
Kealan,Schroeder [7]
;
Meng,Zhao [1]
;
Aparna,Venkatraman [8]
;
Pengxu,Qian [1]
;
Zhenrui,Li [1]
;
Mark,Hembree [2]
;
Ariel,Paulson [2]
;
Zhiquan,He [1]
;
Dong,Xu [9]
;
Thanh-Huyen,Tran [1]
;
Prashant,Deshmukh [1]
;
Chi Thanh,Nguyen [10]
;
Rajeswari M,Kasi [11]
;
Robin,Ryan [1]
;
Melinda,Broward [12]
;
Sheng,Ding [1]
;
Erin,Guest [1]
;
Keith,August [13]
;
Alan S,Gamis [13]
;
Andrew,Godwin [6]
;
G Sitta,Sittampalam [14]
;
Scott J,Weir [15]
;
Linheng,Li [16]
作者单位:
Stowers Institute for Medical Research, Kansas City, MO, USA.
[1]
Children's Mercy Kansas City, Kansas City, MO, USA.
[2]
University of Kansas Medical Center, Kansas City, KS, USA.
[3]
University of Missouri Kansas City School of Medicine, Kansas City, MO, USA.
[4]
High Throughput Screening Laboratory, University of Kansas, Lawrence, KS, USA.
[5]
Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, USA.
[6]
Center for Cell Dynamics, Department of Cell Biology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
[7]
Department of Hepatobiliary and Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
[8]
Key Laboratory of Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, Guangdong, China.
[9]
Center of Stem Cell and Regenerative Medicine and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
[10]
Institute of Hematology, Zhejiang University and Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.
[11]
St. Jude, Memphis, TN, USA.
[12]
Department of Electrical Engineering and Computer Science and C.S. Bond Life Sciences Center, University of Missouri, Columbia, MO, USA.
[13]
Department of Pharmaceutical Sciences, Northeastern University, Boston, MA, US.
[14]
Polymer Program, Institute of Materials Science, University of Connecticut, Storrs, CT, USA.
[15]
Department of Chemistry, University of Connecticut, Storrs, CT, USA.
[16]
School of Pharmaceutical Science, Tsinghua University, Beijing, China.
[17]
Therapeutics for Rare and Neglected Diseases, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
[18]
Department of Cancer Biology, The Institute for Advancing Medical Innovation and University of Kansas Cancer Center, Kansas City, Kansas, USA.
[19]
Stowers Institute for Medical Research, Kansas City, MO, USA. lil@stowers.org.
[20]
Department of Pathology and Laboratory Medicine and Division of Medical Oncology, Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA. lil@stowers.org.
[21]
主题词
动物(Animals);抗生素类, 抗肿瘤(Antibiotics, Antineoplastic);细胞凋亡(Apoptosis);细胞增殖(Cell Proliferation);多柔比星(Doxorubicin);抗药性, 肿瘤(Drug Resistance, Neoplasm);女(雌)性(Female);人类(Humans);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);男(雄)性(Male);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);肿瘤干细胞(Neoplastic Stem Cells);PTEN磷酸水解酶(PTEN Phosphohydrolase);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);肿瘤细胞, 培养的(Tumor Cells, Cultured);Wnt蛋白质类(Wnt Proteins);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);β连环素(beta Catenin)
DOI
10.1038/s41556-020-0507-y
PMID
32313104
发布时间
2024-05-03