New dehydroabietic acid (DHA) derivatives with anticancer activity against HepG2 cancer cell lines as a potential drug targeting EGFR kinase domain. CoMFA study and virtual ligand-based screening.

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作者： Hanane,Zaki ^[1] ; Assia,Belhassan ^[1] ; Mohamed,Benlyas ^[2] ; Tahar,Lakhlifi ^[1] ; Mohammed,Bouachrine ^[1]

作者单位： MCNS Laboratory, Faculty of Science, Moulay Ismail University, Meknes, Morocco. ^[1] Biology Environment and Health Laboratory, Faculty of Science and Technics, Moulay Ismail University, Errachidia, Morocco. ^[2] EST Khenifra, Sultan Moulay Sliman University, Khenifra, Morocco. ^[3]

关键词 3D-QSAR Anticancer activity CoMFA EGFR HepG2 human cancer cell line

主题词药物释放系统(Drug Delivery Systems);癌症早期检测(Early Detection of Cancer);Hep G2细胞(Hep G2 Cells);人类(Humans);配体(Ligands);肿瘤(Neoplasms);量化构效关系(Quantitative Structure-Activity Relationship)

DOI 10.1080/07391102.2020.1759452

PMID 32319344

发布时间 2022-05-31

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准确一般字义偏差语意偏离译文作用小提交