Performance of a novel in vitro assay for skin sensitization based on activation of T lymphocytes.

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作者： Fenxia,Hou ^[1] ; Caihong,Xing ^[1] ; Bin,Li ^[1] ; Juan,Cheng ^[1] ; Wei,Chen ^[1]

作者单位： Department of Toxicology, National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China. ^[1]

关键词 CD69 Jurkat Clone E6-1 human T lymphocyte flow cytometry predictivity skin sensitization potency

主题词动物替代试验(Animal Testing Alternatives);生物学鉴定法(Biological Assay);皮炎, 变应性接触性(Dermatitis, Allergic Contact);人类(Humans);Jurkat细胞(Jurkat Cells);角蛋白细胞(Keratinocytes);淋巴细胞活化(Lymphocyte Activation);结果可重复性(Reproducibility of Results);皮肤(Skin);T淋巴细胞(T-Lymphocytes)

DOI 10.14573/altex.2001312

PMID 32323861

发布时间 2021-07-26

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2020年37卷3期

451-468页

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Performance of a novel in vitro assay for skin sensitization based on activation of T lymphocytes.

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Performance of a novel in vitro assay for skin sensitization based on activation of T lymphocytes.

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