Structure of human DPEP3 in complex with the SC-003 antibody Fab fragment reveals basis for lack of dipeptidase activity.

导出 LinkOut

翻译打印收藏纠错

第一作者： Kristyn,Hayashi

第一单位： Research and Development, AbbVie Inc, South San Francisco, CA 94080, United States.

作者： Kristyn,Hayashi ^[1] ; Kenton L,Longenecker ^[2] ; Patrick,Koenig ^[1] ; Aditi,Prashar ^[1] ; Johannes,Hampl ^[1] ; Vincent,Stoll ^[2] ; Sandro,Vivona ^[3]

作者单位： Research and Development, AbbVie Inc, South San Francisco, CA 94080, United States. ^[1] Research and Development, AbbVie Inc, North Chicago, Illinois, 60064, United States. ^[2] Research and Development, AbbVie Inc, South San Francisco, CA 94080, United States; Research and Development, AbbVie Inc, North Chicago, Illinois, 60064, United States. Electronic address: sandrovivona@gmail.com. ^[3]

关键词 Antibody drug conjugate Enzyme Epitope Metalloprotease Structure–function Zinc

主题词抗体(Antibodies);二肽酶类(Dipeptidases);表位(Epitopes);人类(Humans);免疫轭合物(Immunoconjugates);免疫球蛋白Fab片段(Immunoglobulin Fab Fragments);膜蛋白质类(Membrane Proteins)

DOI 10.1016/j.jsb.2020.107512

PMID 32325220

发布时间 2021-08-02

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交