换一批Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization.
第一作者：
Bo-Ya,Zhou
第一单位：
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Tissue Engineering Research, Shanghai, 200011, China.
作者：
医学主题词
青少年(Adolescent);成年人(Adult);老年人(Aged);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);儿童(Child);胶原(Collagen);剂量效应关系, 药物(Dose-Response Relationship, Drug);女(雌)性(Female);成纤维细胞(Fibroblasts);基因表达调控(Gene Expression Regulation);人类(Humans);吲哚类(Indoles);瘢痕疙瘩(Keloid);MAP激酶信号系统(MAP Kinase Signaling System);男(雄)性(Male);中年人(Middle Aged);磷酰化(Phosphorylation);蛋白激酶抑制剂(Protein Kinase Inhibitors);蛋白激酶类(Protein Kinases);受体, 生长因子(Receptors, Growth Factor);青年人(Young Adult)
DOI
10.1038/s41401-020-0381-y
PMID
32327724
发布时间
2021-06-01
- 浏览0
Acta pharmacologica Sinica
1234-1245页
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