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Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.

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第一作者: Julien,Bryois
第一单位: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
作者单位: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. [1] Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.;UCL Institute of Neurology, Queen Square, London, UK.;Division of Brain Sciences, Department of Medicine, Imperial College, London, UK.;UK Dementia Research Institute at Imperial College, London, UK. [2] Danish Headache Center, Dept of Neurology, Copenhagen University Hospital, Glostrup, Denmark.;Institute of Biological Psychiatry, Copenhagen University Hospital MHC Sct Hans, Roskilde, Denmark.;Novo Nordic Foundations Center for Protein Research, Copenhagen University, Copenhagen, Denmark. [3] Danish Headache Center, Dept of Neurology, Copenhagen University Hospital, Glostrup, Denmark. [4] Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.;School of Psychology, Curtin University, Perth, Western Australia, Australia.;Division of Paediatrics, School of Medicine, The University of Western Australia, Perth, Western Australia, Australia. [5] Division of Brain Sciences, Department of Medicine, Imperial College, London, UK.;UK Dementia Research Institute at Imperial College, London, UK. [6] Department of Psychiatry, University of Iowa Carver College of Medicine, University of Iowa, Iowa City, IA, USA. [7] Institute of Psychiatry, MRC Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.;National Institute for Health Research Biomedical Research Centre, South London and Maudsley National Health Service Trust, London, UK. [8] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.;Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.;Department of Nutrition, University of North Carolina, Chapel Hill, NC, USA. [9] Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden. [10] Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden. jens.hjerling-leffler@ki.se. [11] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. patrick.sullivan@ki.se.;Department of Genetics, University of North Carolina, Chapel Hill, NC, USA. patrick.sullivan@ki.se. [12]
DOI 10.1038/s41588-020-0610-9
PMID 32341526
发布时间 2025-12-14
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