Plasma cell-free DNA variant analysis compared with methylated DNA analysis in renal cell carcinoma.

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作者： Kathryn,Lasseter ^[1] ; Amin H,Nassar ^[1] ; Lana,Hamieh ^[2] ; Jacob E,Berchuck ^[1] ; Pier Vitale,Nuzzo ^[2] ; Keegan,Korthauer ^[2] ; Atul B,Shinagare ^[2] ; Barbara,Ogorek ^[3] ; Rana,McKay ^[4] ; Aaron R,Thorner ^[1] ; Gwo-Shu Mary,Lee ^[5] ; David A,Braun ^[2] ; Rupal S,Bhatt ^[6] ; Matthew,Freedman ^[2] ; Toni K,Choueiri ^[2] ; David J,Kwiatkowski ^[7]

作者单位： Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. ^[1] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. ^[2] Department of Statistics, University of British Columbia, Vancouver, BC, USA. ^[3] Department of Radiology, Brigham and Women's Hospital/ Dana-Farber Cancer Institute, Boston, MA, USA. ^[4] Moores Cancer Center, UC San Diego Health, San Diego, CA, USA. ^[5] Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, MA, USA. ^[6] Division of Hematology Oncology and Cancer Biology, Beth Israel Deaconess Medical Center, Boston, MA, USA. ^[7] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. freedman@broadinstitute.org. ^[8] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Toni_Choueiri@dfci.harvard.edu. ^[9] Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. dk@rics.bwh.harvard.edu. ^[10]

关键词 clonal hematopoiesis genomic alterations massively parallel sequencing plasma cell-free DNA renal cell carcinoma

主题词癌, 肾细胞(Carcinoma, Renal Cell);DNA(DNA);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);肾肿瘤(Kidney Neoplasms);血浆(Plasma)

DOI 10.1038/s41436-020-0801-x

PMID 32341571

发布时间 2022-02-10

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