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Mitochondrial Complex 1, Sigma 1, and Synaptic Vesicle 2A in Early Drug-Naive Parkinson's Disease.

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第一作者： Heather,Wilson

第一单位： Neurodegeneration Imaging Group, University of Exeter Medical School, London, UK.;Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

作者： Heather,Wilson ^[1] ; Gennaro,Pagano ^[2] ; Edoardo Rosario,de Natale ^[1] ; Ayla,Mansur ^[3] ; Silvia Paola,Caminiti ^[2] ; Sotirios,Polychronis ^[2] ; Lefkos T,Middleton ^[4] ; Geraint,Price ^[5] ; Karl F,Schmidt ^[6] ; Roger N,Gunn ^[7] ; Eugenii A,Rabiner ^[8] ; Marios,Politis ^[9]

作者单位： Neurodegeneration Imaging Group, University of Exeter Medical School, London, UK.;Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK. ^[1] Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK. ^[2] Invicro, Centre for Imaging Sciences, Hammersmith Hospital, London, UK.;Division of Brain Sciences, Department of Medicine, Imperial College London, UK. ^[3] School of Public Health, Imperial College London, UK.;Public Health Directorate, Imperial College NHS Healthcare Trust, London, UK.;MINDMAPS Consortium, London, UK. ^[4] School of Public Health, Imperial College London, UK.;MINDMAPS Consortium, London, UK. ^[5] Celgene, Cambridge, Massachusetts, USA. ^[6] Invicro, Centre for Imaging Sciences, Hammersmith Hospital, London, UK.;Division of Brain Sciences, Department of Medicine, Imperial College London, UK.;MINDMAPS Consortium, London, UK. ^[7] Invicro, Centre for Imaging Sciences, Hammersmith Hospital, London, UK.;MINDMAPS Consortium, London, UK.;Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. ^[8] Neurodegeneration Imaging Group, University of Exeter Medical School, London, UK.;Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.;MINDMAPS Consortium, London, UK. ^[9]

关键词 Parkinson's disease mitochondria molecular biomarkers positron emission tomography synaptic vesicle protein

主题词横断面研究(Cross-Sectional Studies);人类(Humans);帕金森病(Parkinson Disease);药用制剂(Pharmaceutical Preparations);正电子发射断层显像术(Positron-Emission Tomography);突触小泡(Synaptic Vesicles)

DOI 10.1002/mds.28064

PMID 32347983

发布时间 2021-04-27

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