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Multiple Adenosine-Dopamine (A2A-D2 Like) Heteroreceptor Complexes in the Brain and Their Role in Schizophrenia.

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第一作者： Dasiel O,Borroto-Escuela

第一单位： Department of Neuroscience, Karolinska Institutet, 17170 Stockholm, Sweden.;Observatorio Cubano de Neurociencias, Grupo Bohío-Estudio, 62100 Yaguajay, Cuba.

作者： Dasiel O,Borroto-Escuela ^[1] ; Luca,Ferraro ^[2] ; Manuel,Narvaez ^[3] ; Sergio,Tanganelli ^[4] ; Sarah,Beggiato ^[2] ; Fang,Liu ^[5] ; Alicia,Rivera ^[6] ; Kjell,Fuxe ^[7]

作者单位： Department of Neuroscience, Karolinska Institutet, 17170 Stockholm, Sweden.;Observatorio Cubano de Neurociencias, Grupo Bohío-Estudio, 62100 Yaguajay, Cuba. ^[1] Department of Life sciences and Biotechnology, University of Ferrara, 44121 Ferrara, Italy. ^[2] Facultad de Medicina, Instituto de Investigacion de Málaga, Universidad de Malaga, 29016 Malaga, Spain. ^[3] Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy. ^[4] Campbell Research, Centre for Addiction and Mental Health Institute, University of Toronto, Toronto, ON MS5 1A1, Canada. ^[5] Department of Cell Biology, University of Malaga, Instituto de Investigación Biomédica (IBIMA), 29016 Malaga, Spain. ^[6] Department of Neuroscience, Karolinska Institutet, 17170 Stockholm, Sweden. ^[7]

关键词 A2A-D2 heteroreceptor complexes adenosine receptors brain heterobivalent drugs novel pharmacology schizophrenia sigma 1 receptor

医学主题词腺苷(Adenosine);脑(Brain);中枢神经系统(Central Nervous System);多巴胺(Dopamine);人类(Humans);神经元(Neurons);受体, 腺苷A2A(Receptor, Adenosine A2A);受体, 多巴胺D2(Receptors, Dopamine D2);精神分裂症(Schizophrenia)

DOI 10.3390/cells9051077

PMID 32349279

发布时间 2021-03-16

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