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首页> FASEB journal : official publication of the Federation of American Societies for Experimental Biology> EDAG mediates Hsp70 nuclear localization in erythroblasts and rescues dyserythropoiesis in myelodysplastic syndrome.

EDAG mediates Hsp70 nuclear localization in erythroblasts and rescues dyserythropoiesis in myelodysplastic syndrome.

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作者： Xiao-Ming,Dong ^[1] ; Ke,Zhao ^[2] ; Wei-Wei,Zheng ^[3] ; Cheng-Wang,Xu ^[1] ; Mei-Jiang,Zhang ^[1] ; Rong-Hua,Yin ^[1] ; Rui,Gao ^[1] ; Liu-Jun,Tang ^[2] ; Jin-Fang,Liu ^[1] ; Hui,Chen ^[1] ; Yi-Qun,Zhan ^[1] ; Miao,Yu ^[1] ; Chang-Hui,Ge ^[1] ; Hui-Ying,Gao ^[1] ; Xiu,Li ^[1] ; Teng,Luo ^[4] ; Hong-Mei,Ning ^[1] ; Xiao-Ming,Yang ^[5] ; Chang-Yan,Li ^[1]

作者单位： State Key Laboratory of Proteomics, Beijing Proteome Research Center, Beijing Institute of Lifeomics, Beijing, China. ^[1] Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin, China. ^[2] College of Life Sciences, Shaanxi Normal University, Xi'an, China. ^[3] Department of Experimental Hematology and Biochemistry, Beijing Institute of Radiation Medicine, Beijing, China. ^[4] School of Postgraduate, Anhui Medical University, Hefei, China. ^[5] Department of Hematopoietic Stem Cell Transplantation, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China. ^[6]

关键词 EDAG Hsp70 dyserythropoiesis myelodysplastic syndrome nuclear localization

主题词细胞凋亡(Apoptosis);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);细胞分化(Cell Differentiation);细胞核(Cell Nucleus);细胞, 培养的(Cells, Cultured);细胞质(Cytoplasm);幼红细胞(Erythroblasts);红细胞生成(Erythropoiesis);基因表达调控(Gene Expression Regulation);HSP70热休克蛋白质类(HSP70 Heat-Shock Proteins);血液病(Hematologic Diseases);人类(Humans);骨髓增生异常综合征(Myelodysplastic Syndromes);核蛋白质类(Nuclear Proteins)

DOI 10.1096/fj.201902946R

PMID 32350948

发布时间 2021-01-15

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FASEB journal : official publication of the Federation of American Societies for Experimental Biology

FASEB journal

2020年34卷6期

8416-8427页

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