Xanthenedione (and intermediates involved in their synthesis) inhibit Zika virus migration to the central nervous system in murine neonatal models.

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第一作者： Ítalo Esposti,Poly da Silva

第一单位： Laboratory of Molecular Immunovirology, General Biology Department, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil.

作者： Ítalo Esposti,Poly da Silva ^[1] ; Milene,Lopes da Silva ^[2] ; Roberto Sousa,Dias ^[1] ; Edjon Gonçalves,Santos ^[1] ; Maria Cecília,Brangioni de Paula ^[1] ; André,Silva de Oliveira ^[3] ; Ana Flávia,Costa da Silveira Oliveira ^[3] ; Fabrício,Marques de Oliveira ^[4] ; Cynthia,Canedo da Silva ^[5] ; Róbson Ricardo,Teixeira ^[6] ; Sérgio,Oliveira de Paula ^[7]

作者单位： Laboratory of Molecular Immunovirology, General Biology Department, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil. ^[1] Chemistry Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil. ^[2] Instituto Federal Do Norte de Minas Gerais - Campus Diamantina, Diamantina, Minas Gerais, Brazil. ^[3] Instituto Federal de Minas Gerais (IFMG), Campus Ouro Branco, Rua Afonso Ouro Branco, Minas Gerais, Brazil. ^[4] Laboratory of Microbiology, Microbiology Department, Federal University of Viçosa, Brazil. ^[5] Chemistry Department, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil. Electronic address: robsonr.teixeira@ufv.br. ^[6] Laboratory of Molecular Immunovirology, General Biology Department, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil. Electronic address: depaula@ufv.br. ^[7]

关键词 Antiviral Flavivirus Ketones Xanthenodiones Zika virus