High-dose MTX110 (soluble panobinostat) safely administered into the fourth ventricle in a nonhuman primate model.

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第一作者： David I,Sandberg

第一单位： 1Departments of Pediatric Surgery and.;2Neurosurgery.

作者： David I,Sandberg ^[1] ; Natasha,Kharas ^[1] ; Bangning,Yu ^[1] ; Christopher F,Janssen ^[2] ; Amanda,Trimble ^[2] ; Leomar Y,Ballester ^[3] ; Rajan,Patel ^[4] ; Afroz S,Mohammad ^[5] ; William F,Elmquist ^[5] ; Rachael W,Sirianni ^[6]

作者单位： 1Departments of Pediatric Surgery and.;2Neurosurgery. ^[1] 3Center for Laboratory Animal Medicine and Care, and. ^[2] 2Neurosurgery.;4Departments of Pathology and Laboratory Medicine and. ^[3] 5Diagnostic and Interventional Imaging, McGovern Medical School, The University of Texas Health Science Center at Houston, Texas; and. ^[4] 6Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota. ^[5] 2Neurosurgery. ^[6]

关键词 brain tumor fourth ventricle intraventricular medulloblastoma oncology panobinostat primate

DOI 10.3171/2020.2.PEDS19786

PMID 32357333

发布时间 2024-08-13

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