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Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk.

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第一作者: Pooja Middha,Kapoor
第一单位: Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.;Faculty of Medicine, University of Heidelberg, Heidelberg, Germany.
作者: Pooja Middha,Kapoor [1] ; Nasim,Mavaddat [2] ; Parichoy Pal,Choudhury [3] ; Amber N,Wilcox [4] ; Sara,Lindström [5] ; Sabine,Behrens [6] ; Kyriaki,Michailidou [7] ; Joe,Dennis [2] ; Manjeet K,Bolla [2] ; Qin,Wang [2] ; Audrey,Jung [6] ; Zomoroda,Abu-Ful [8] ; Thomas,Ahearn [3] ; Irene L,Andrulis [9] ; Hoda,Anton-Culver [10] ; Volker,Arndt [11] ; Kristan J,Aronson [12] ; Paul L,Auer [13] ; Laura E Beane,Freeman [3] ; Heiko,Becher [14] ; Matthias W,Beckmann [15] ; Alicia,Beeghly-Fadiel [16] ; Javier,Benitez [17] ; Leslie,Bernstein [18] ; Stig E,Bojesen [19] ; Hiltrud,Brauch [20] ; Hermann,Brenner [21] ; Thomas,Brüning [22] ; Qiuyin,Cai [16] ; Daniele,Campa [23] ; Federico,Canzian [24] ; Angel,Carracedo [25] ; Brian D,Carter [26] ; Jose E,Castelao [27] ; Stephen J,Chanock [3] ; Nilanjan,Chatterjee [28] ; Georgia,Chenevix-Trench [29] ; Christine L,Clarke [30] ; Fergus J,Couch [31] ; Angela,Cox [32] ; Simon S,Cross [33] ; Kamila,Czene [34] ; James Y,Dai [35] ; H Shelton,Earp [36] ; Arif B,Ekici [37] ; A Heather,Eliassen [38] ; Mikael,Eriksson [34] ; D Gareth,Evans [39] ; Peter A,Fasching [40] ; Jonine,Figueroa [41] ; Lin,Fritschi [42] ; Marike,Gabrielson [34] ; Manuela,Gago-Dominguez [43] ; Chi,Gao [44] ; Susan M,Gapstur [26] ; Mia M,Gaudet [26] ; Graham G,Giles [45] ; Anna,González-Neira [46] ; Pascal,Guénel [47] ; Lothar,Haeberle [48] ; Christopher A,Haiman [49] ; Niclas,Håkansson [50] ; Per,Hall [51] ; Ute,Hamann [52] ; Sigrid,Hatse [53] ; Jane,Heyworth [54] ; Bernd,Holleczek [55] ; Robert N,Hoover [3] ; John L,Hopper [56] ; Anthony,Howell [57] ; David J,Hunter [58] ; ABCTB Investigators [59] ; kConFab/AOCS Investigators [60] ; Esther M,John [6] ; Michael E,Jones [61] ; Rudolf,Kaaks [62] ; Renske,Keeman [63] ; Cari M,Kitahara [3] ; Yon-Dschun,Ko [59] ; Stella,Koutros [64] ; Allison W,Kurian [65] ; Diether,Lambrechts [49] ; Loic,Le Marchand [8] ; Eunjung,Lee [62] ; Flavio,Lejbkowicz [66] ; Martha,Linet [67] ; Jolanta,Lissowska [68] ; Ana,Llaneza [69] ; Robert J,MacInnis [70] ; Maria Elena,Martinez [71] ; Tabea,Maurer [18] ; Catriona,McLean [39] ; Susan L,Neuhausen [72] ; William G,Newman [73] ; Aaron,Norman [74] ; Katie M,O'Brien [72] ; Andrew F,Olshan [75] ; Janet E,Olson [76] ; Håkan,Olsson [77] ; Nick,Orr [78] ; Charles M,Perou [72] ; Guillermo,Pita [35] ; Eric C,Polley [8] ; Ross L,Prentice [8] ; Gad,Rennert [79] ; Hedy S,Rennert [73] ; Kathryn J,Ruddy [80] ; Dale P,Sandler [60] ; Christobel,Saunders [81] ; Minouk J,Schoemaker [82] ; Ben,Schöttker [72] ; Fredrick,Schumacher [83] ; Christopher,Scott [16] ; Rodney J,Scott [84] ; Xiao-Ou,Shu [85] ; Ann,Smeets [86] ; Melissa C,Southey [87] ; John J,Spinelli [88] ; Jennifer,Stone [89] ; Anthony J,Swerdlow [90] ; Rulla M,Tamimi [74] ; Jack A,Taylor [91] ; Melissa A,Troester [39] ; Celine M,Vachon [5] ; Elke M,van Veen [92] ; Xiaoliang,Wang [93] ; Clarice R,Weinberg [94] ; Caroline,Weltens [95] ; Walter,Willett [96] ; Stacey J,Winham [3] ; Alicja,Wolk [16] ; Xiaohong R,Yang [10] ; Wei,Zheng [97] ; Argyrios,Ziogas [98] ; Alison M,Dunning [99] ; Paul D P,Pharoah [44] ; Marjanka K,Schmidt [98] ; Peter,Kraft [83] ; Douglas F,Easton [3] ; Roger L,Milne [100] ; Montserrat,García-Closas ; Jenny,Chang-Claude
作者单位: Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.;Faculty of Medicine, University of Heidelberg, Heidelberg, Germany. [1] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. [2] Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. [3] Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.;Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [4] Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA.;Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. [5] Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. [6] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.;Biostatistics Unit and the Cyprus, School of Molecular Medicine, Cyprus Institute of Neurology & Genetics, Nicosia, Cyprus. [7] Clalit National Cancer Control Center, Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel. [8] Fred A. Litwin Center for Cancer Genetics, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, ON, Canada.;Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. [9] Department of Epidemiology, Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA, USA. [10] Division of Clinical Epidemiology and Aging Research, C070, German Cancer Research Center (DKFZ), Heidelberg, Germany. [11] Department of Public Health Sciences and Cancer Research Institute, Queen's University, Kingston, ON, Canada. [12] Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.;Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA. [13] Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.;Institute of Biometry and Clinical Epidemiology, Charité-Universitätsmedizin Berlin, Berlin, Germany. [14] Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany. [15] Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA. [16] Centro de Investigación en Red de Enfermedades Raras (CIBERER), Madrid, Spain.;Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain. [17] Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA. [18] Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.;Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.;Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [19] Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.;Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.;Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.;Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.;iFIT-Cluster of Excellence, University of Tuebingen, Tuebingen, Germany.;German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. [20] Division of Clinical Epidemiology and Aging Research, C070, German Cancer Research Center (DKFZ), Heidelberg, Germany.;German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.;Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany. [21] Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Bochum, Germany. [22] Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.;Department of Biology, University of Pisa, Pisa, Italy. [23] Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany. [24] Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.;Centro de Investigación en Red de Enfermedades Raras (CIBERER) y Centro Nacional de Genotipado (CEGEN-PRB2), Universidad de Santiago de Compostela, Santiago De Compostela, Spain. [25] Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, USA. [26] Oncology and Genetics Unit, Instituto de Investigacion Sanitaria Galicia Sur (IISGS), Xerencia de Xestion Integrada de Vigo-SERGAS, Vigo, Spain. [27] Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.;Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.;Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. [28] Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. [29] Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia. [30] Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. [31] Sheffield Institute for Nucleic Acids (SInFoNiA), Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK. [32] Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield, UK. [33] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. [34] Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. [35] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [36] Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. [37] Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.;Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. [38] Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.;North West Genomics Laboratory Hub, Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. [39] Department of Gynecology and Obstetrics, Comprehensive Cancer Center ER-EMN, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.;David Geffen School of Medicine, Department of Medicine Division of Hematology and Oncology, University of California at Los Angeles, Los Angeles, CA, USA. [40] Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.;Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh Medical School, Edinburgh, UK.;Cancer Research UK Edinburgh Centre, Edinburgh, UK. [41] School of Public Health, Curtin University, Perth, Western Australia, Australia. [42] Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.;Moores Cancer Center, University of California San Diego, La Jolla, CA, USA. [43] Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.;Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. [44] Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.;Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.;Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.;Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.;iFIT-Cluster of Excellence, University of Tuebingen, Tuebingen, Germany.;German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.;Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.;Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.;Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia. [45] Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain. [46] Cancer & Environment Group, Center for Research in Epidemiology and Population Health (CESP), INSERM, University Paris-Sud, University Paris-Saclay, Villejuif, France. [47] Department of Gynaecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, Erlangen, Germany. [48] Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. [49] Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. [50] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.;Department of Oncology, Södersjukhuset, Stockholm, Sweden. [51] Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. [52] Laboratory of Experimental Oncology (LEO), Department of Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium. [53] School of Population and Global Health, The University of Western Australia, Perth, Western Australia, Australia. [54] Saarland Cancer Registry, Saarbrücken, Germany. [55] Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia. [56] Division of Cancer Sciences, University of Manchester, Manchester, UK. [57] Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.;Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.;Nuffield Department of Population Health, University of Oxford, Oxford, UK. [58] Division of Oncology, Departments of Epidemiology & Population Health and of Medicine, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA. [59] Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK. [60] Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. [61] Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA. [62] Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Germany. [63] VIB Center for Cancer Biology, VIB, Leuven, Belgium.;Laboratory for Translational Genetics, Department of Human Genetics, University of Leuven, Leuven, Belgium. [64] Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA. [65] Department of Cancer Epidemiology and Prevention, M. Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland. [66] General and Gastroenterology Surgery Service, Hospital Universitario Central de Asturias, Oviedo, Spain. [67] Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.;Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia. [68] Moores Cancer Center, University of California San Diego, La Jolla, CA, USA.;Department of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, USA. [69] Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany. [70] Anatomical Pathology, The Alfred Hospital, Melbourne, Victoria, Australia. [71] Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA. [72] Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA. [73] Department of Epidemiology, Gillings School of Global Public Health and UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [74] Department of Cancer Epidemiology, Clinical Sciences, Lund University, Lund, Sweden. [75] Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, Ireland, UK. [76] Department of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. [77] Human Genotyping-CEGEN Unit, Human Cancer Genetic Program, Spanish National Cancer Research Centre, Madrid, Spain. [78] Department of Oncology, Mayo Clinic, Rochester, MN, USA. [79] School of Medicine, University of Western Australia, Perth, Western Australia, Australia. [80] Division of Clinical Epidemiology and Aging Research, C070, German Cancer Research Center (DKFZ), Heidelberg, Germany.;Network Aging Research, University of Heidelberg, Heidelberg, Germany. [81] Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA. [82] Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.;Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.;Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.;Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.;iFIT-Cluster of Excellence, University of Tuebingen, Tuebingen, Germany.;German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.;Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.;Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.;Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.;Division of Molecular Medicine, Pathology North, John Hunter Hospital, Newcastle, New South Wales, Australia.;Discipline of Medical Genetics, School of Biomedical Sciences and Pharmacy, Faculty of Health, University of Newcastle, Callaghan, New South Wales, Australia.;Hunter Medical Research Institute, John Hunter Hospital, Newcastle, New South Wales, Australia. [83] Department of Surgical Oncology, University Hospitals Leuven, Leuven, Belgium. [84] Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, Australia.;Department of Clinical Pathology, The University of Melbourne, Melbourne, Victoria, Australia.;Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria, Australia. [85] Population Oncology, BC Cancer, Vancouver, BC, Canada.;School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada. [86] Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.;The Curtin UWA Centre for Genetic Origins of Health and Disease, Curtin University and University of Western Australia, Perth, Western Australia, Australia. [87] Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.;Division of Breast Cancer Research, The Institute of Cancer Research, London, UK. [88] Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.;Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.;Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. [89] Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA.;Epigenetic and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA. [90] Department of Health Science Research, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA. [91] Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA. [92] Leuven Multidisciplinary Breast Center, Department of Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium. [93] Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.;Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA.;Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. [94] Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic, Rochester, MN, USA. [95] Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.;Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. [96] Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. [97] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.;Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK. [98] Division of Molecular Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.;Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands. [99] Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.;Cancer Epidemiology Group, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany. [100]
DOI 10.1093/jnci/djaa056
PMID 32359158
发布时间 2026-04-05
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