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Intellectual and Developmental Disabilities Research Centers: A Multidisciplinary Approach to Understand the Pathogenesis of Methyl-CpG Binding Protein 2-related Disorders.

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第一作者： Michela,Fagiolini

第一单位： Children's Hospital Intellectual and Developmental Disabilities Research Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: michela.fagiolini@childrens.harvard.edu.

作者： Michela,Fagiolini ^[1] ; Annarita,Patrizi ^[2] ; Jocelyn,LeBlanc ^[2] ; Lee-Way,Jin ^[3] ; Izumi,Maezawa ^[3] ; Sarah,Sinnett ^[4] ; Steven J,Gray ^[4] ; Sophie,Molholm ^[5] ; John J,Foxe ^[6] ; Michael V,Johnston ^[7] ; Sakkubai,Naidu ^[7] ; Mary,Blue ^[7] ; Ahamed,Hossain ^[7] ; Shilpa,Kadam ^[7] ; Xinyu,Zhao ^[8] ; Quiang,Chang ^[8] ; Zhaolan,Zhou ^[9] ; Huda,Zoghbi ^[10]

作者单位： Children's Hospital Intellectual and Developmental Disabilities Research Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: michela.fagiolini@childrens.harvard.edu. ^[1] Children's Hospital Intellectual and Developmental Disabilities Research Center, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. ^[2] UC Davis MIND Institute, University of California, Sacramento, CA, USA. ^[3] UNC Intellectual and Developmental Disabilities Research Center, University of North Carolina, Gene Therapy Center and Dept. of Ophthalmology, Chapel Hill, NC, USA; Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX, USA. ^[4] The Cognitive Neurophysiology Laboratory, Departments of Pediatrics, Neuroscience, and Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY, USA. ^[5] The Cognitive Neurophysiology Laboratory, Ernest J. Del Monte Institute for Neuroscience, Department of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA. ^[6] Kennedy Krieger Institute Intellectual and Developmental Disabilities Research Center/Hugo Moser Research Institute at Kennedy Krieger and Johns Hopkins School of Medicine, USA. ^[7] Waisman Center, University of Wisconsin-Madison, Madison, WI, USA. ^[8] Department of Genetic, Epigenetic Institute, University of Pennsylvania Perelman School of Medicine, Intellectual and Developmental Disabilities Research Center, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA. ^[9] Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX, USA; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA; Department of Neuroscience, Baylor College of Medicine, Houston, TX, USA; Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX, USA. ^[10]

关键词 animal models biomarkers neurodevelopmental disorders signaling pathways translational