Reprogramming Axial Level Identity to Rescue Neural-Crest-Related Congenital Heart Defects.

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作者： Shashank,Gandhi ^[1] ; Max,Ezin ^[2] ; Marianne E,Bronner ^[3]

作者单位： Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. ^[1] Department of Biology, Loyola Marymount University, Los Angeles, CA 90045, USA. ^[2] Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: mbronner@caltech.edu. ^[3]

关键词 aorticopulmonary septum cardiac crest subcircuit cardiac neural crest congenital birth defects ectomesenchymal fate heart development outflow tract persistent truncus arteriosus reprogramming specification

主题词动物(Animals);鸡胚(Chick Embryo);心脏缺损, 先天性(Heart Defects, Congenital);同源盒结构域蛋白质类(Homeodomain Proteins);神经嵴(Neural Crest);原癌基因蛋白质c-ets-1(Proto-Oncogene Protein c-ets-1);SOXE转录因子类(SOXE Transcription Factors)

DOI 10.1016/j.devcel.2020.04.005

PMID 32369742

发布时间 2021-05-04

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