An unexpected 2-histidine phosphoesterase activity of suppressor of T-cell receptor signaling protein 1 contributes to the suppression of cell signaling.
作者:
关键词
2-histidine (2H) phosphoesterase2H phosphoesterase2′,3′-cyclic nicotinamide adenine dinucleotide phosphate (NADcP)Dectin-1 receptorNADcPSuppressor of TCR Signaling-1/2Suppressor of TCR signaling-1 (Sts-1)T-cell receptor (TCR)cell signalingcyclic nucleotideenzymephosphodiesterasephosphodiesterasessignal transduction
主题词
氨基酸特征结构(Amino Acid Motifs);动物(Animals);催化域(Catalytic Domain);人类(Humans);干扰素γ(Interferon-gamma);动力学(Kinetics);外源凝集素类, C型(Lectins, C-Type);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);诱变, 定点(Mutagenesis, Site-Directed);NADP(NADP);蛋白质酪氨酸磷酸酶类(Protein Tyrosine Phosphatases);受体, 抗原, T细胞(Receptors, Antigen, T-Cell);序列比对(Sequence Alignment);信号传导(Signal Transduction);底物特异性(Substrate Specificity);T淋巴细胞(T-Lymphocytes)
DOI
10.1074/jbc.RA120.013482
PMID
32371395
发布时间
2021-09-14
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The Journal of biological chemistry
8514-8523页
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