Chromogranin A (CGA)-derived polypeptide (CGA<sub>47-66</sub>) inhibits TNF-α-induced vascular endothelial hyper-permeability through SOC-related Ca<sup>2+</sup> signaling.
第一作者:
Li,Luo
第一单位:
Department of Emergency, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, PR China; Department of Emergency, The Third People's Hospital of Chengdu, The Second Affiliated Chengdu Clinical College of Chongqing Medical University, Chengdu, Sichuan 610031, PR China.
作者:
主题词
肌动蛋白类(Actins);钙(Calcium);钙信号(Calcium Signaling);细胞系, 转化(Cell Line, Transformed);细胞膜通透性(Cell Membrane Permeability);嗜铬粒蛋白质A(Chromogranin A);扩散盒, 培养(Diffusion Chambers, Culture);剂量效应关系, 药物(Dose-Response Relationship, Drug);内皮细胞(Endothelial Cells);基因表达调控(Gene Expression Regulation);人类(Humans);肌醇1,4,5-三磷酸(Inositol 1,4,5-Trisphosphate);肌球蛋白轻链磷酸酶(Myosin-Light-Chain Phosphatase);膜片钳术(Patch-Clamp Techniques);肽碎片(Peptide Fragments);磷酰化(Phosphorylation);TRPC阳离子通道(TRPC Cation Channels);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1016/j.peptides.2020.170297
PMID
32380199
发布时间
2021-06-30
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