APPA (apocynin and paeonol) modulates pathological aspects of human neutrophil function, without supressing antimicrobial ability, and inhibits TNFα expression and signalling.
作者:
主题词
苯乙酮类(Acetophenones);消炎药(Anti-Inflammatory Agents);细胞凋亡(Apoptosis);细胞, 培养的(Cells, Cultured);细胞因子类(Cytokines);剂量效应关系, 药物(Dose-Response Relationship, Drug);复方合剂(Drug Combinations);人类(Humans);炎症(Inflammation);中性白细胞(Neutrophils);活性氧(Reactive Oxygen Species);信号传导(Signal Transduction);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1007/s10787-020-00715-5
PMID
32383062
发布时间
2024-03-29
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Inflammopharmacology
1223-1235页
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