Evaluation of the Physico-mechanical Properties and Electrostatic Charging Behavior of Different Capsule Types for Inhalation Under Distinct Environmental Conditions.

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作者： Joana T,Pinto ^[1] ; Thomas,Wutscher ^[1] ; Milica,Stankovic-Brandl ^[2] ; Sarah,Zellnitz ^[1] ; Stefano,Biserni ^[1] ; Alberto,Mercandelli ^[3] ; Mirjam,Kobler ^[3] ; Francesca,Buttini ^[4] ; Laura,Andrade ^[5] ; Veronica,Daza ^[6] ; Susana,Ecenarro ^[6] ; Laura,Canalejas ^[7] ; Amrit,Paudel ^[7]

作者单位： Research Center Pharmaceutical Engineering (RCPE) GmbH, Inffeldgasse 13, 8010, Graz, Austria. ^[1] Institute for Process and Particle Engineering, Graz University of Technology, Inffeldgasse 13/II, 8010, Graz, Austria. ^[2] MG2, Via del Savena 18, 40065 Pian di Macina di Pianoro, Bologna, Italy. ^[3] MEGGLE Excipients and Technology, Megglestraße 6-12, 83512, Wasserburg, Germany. ^[4] Food and Drug Department, University of Parma, Parco delle Scienze 27, 43121, Parma, Italy. ^[5] Laboratorios Liconsa, S.A. Avenida Miralcampo 7, 19200, Azuqueca de Henares, Guadalajara, Spain. ^[6] Qualicaps, Avda. Monte Valdelatas 4, 28108 Alcobendas, Madrid, Spain. ^[7] Research Center Pharmaceutical Engineering (RCPE) GmbH, Inffeldgasse 13, 8010, Graz, Austria. amrit.paudel@rcpe.at. ^[8] Institute for Process and Particle Engineering, Graz University of Technology, Inffeldgasse 13/II, 8010, Graz, Austria. amrit.paudel@rcpe.at. ^[9]

关键词 dry powder inhaler (DPI)gelatin hydroxypropyl methylcellulose (HPMC)tribo-charging water