Real-world data on efficacy and safety of obinutuzumab plus chlorambucil, rituximab plus chlorambucil, and rituximab plus bendamustine in the frontline treatment of chronic lymphocytic leukemia: The GO-CLLEAR Study by the Czech CLL Study Group.

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作者： Anna,Panovská ^[1] ; Lucie,Němcová ^[1] ; Lucie,Nekvindová ^[2] ; Martin,Špaček ^[3] ; Martin,Šimkovič ^[4] ; Tomáš,Papajík ^[5] ; Martin,Brejcha ^[6] ; Daniel,Lysák ^[7] ; Jana,Zuchnická ^[8] ; Jan,Novák ^[9] ; David,Starostka ^[10] ; Hynek,Poul ^[11] ; Filip,Vrbacký ^[4] ; Pavel,Vodárek ^[4] ; Renata,Urbanová ^[5] ; Karla,Plevová ^[1] ; Šárka,Pospíšilová ^[12] ; Stanislava,Mašlejová ^[1] ; Yvona,Brychtová ^[12] ; Eva,Koriťáková ^[1] ; Lukáš,Smolej ^[1] ; Michael,Doubek ^[2]

作者单位： Department of Internal Medicine-Hematology and Oncology, University Hospital and Masaryk University, Brno, Czech Republic. ^[1] Institute of Biostatistics and Analyses, Ltd., Brno, Czech Republic. ^[2] 1st Department of Medicine-Department of Hematology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic. ^[3] 4th Department of Internal Medicine-Hematology, University Hospital and Charles University Faculty of Medicine, Hradec Králové, Czech Republic. ^[4] Department of Hematooncology, University Hospital, Olomouc, Czech Republic. ^[5] Oncology Center, Nový Jičín, Czech Republic. ^[6] Department of Hematology and Oncology, University Hospital, Plzeň, Czech Republic. ^[7] Department of Hematology, University Hospital, Ostrava, Czech Republic. ^[8] Department of Internal Medicine and Hematology, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University, Prague, Czech Republic. ^[9] Department of Hematology, Havirov Hospital and Polyclinic, Havířov, Czech Republic. ^[10] Department of Hematology, Hospital Pelhřimov, Pelhřimov, Czech Republic. ^[11] Central European Institute of Technology, Masaryk University, Brno, Czech Republic. ^[12]

关键词 CIRS CLL frontline treatment obinutuzumab-chlorambucil rituximab-bendamustine rituximab-chlorambucil