The Oral Bioavailability and Metabolism of Midazolam in Stable Critically Ill Children: A Pharmacokinetic Microtracing Study.

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第一作者： Bianca D,van Groen

第一单位： Intensive Care and Pediatric Surgery, Erasmus Medical Center - Sophia Children's Hospital, Rotterdam, The Netherlands.

作者： Bianca D,van Groen ^[1] ; Elke H J,Krekels ^[2] ; Miriam G,Mooij ^[3] ; Esther,van Duijn ^[4] ; Wouter H J,Vaes ^[4] ; Albert D,Windhorst ^[5] ; Joost,van Rosmalen ^[6] ; Stan J F,Hartman ^[7] ; N Harry,Hendrikse ^[5] ; Birgit C P,Koch ^[8] ; Karel,Allegaert ^[9] ; Dick,Tibboel ^[1] ; Catherijne A J,Knibbe ^[10] ; Saskia N,de Wildt ^[11]

作者单位： Intensive Care and Pediatric Surgery, Erasmus Medical Center - Sophia Children's Hospital, Rotterdam, The Netherlands. ^[1] Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands. ^[2] Department of Pediatrics, Leiden University Medical Centre, Leiden, The Netherlands. ^[3] TNO, Zeist, The Netherlands. ^[4] Amsterdam University Medical Centers - Location VU Medical Center, Amsterdam, The Netherlands. ^[5] Department of Biostatistics, Erasmus Medical Center, Rotterdam, the Netherlands. ^[6] Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands. ^[7] Department of Hospital Pharmacy, Erasmus Medical Center, Rotterdam, The Netherlands. ^[8] Department of Hospital Pharmacy, Erasmus Medical Center, Rotterdam, The Netherlands.;Katholieke Universiteit Leuven, Leuven, Belgium. ^[9] Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands.;St Antonius Hospital, Nieuwegein, The Netherlands. ^[10] Intensive Care and Pediatric Surgery, Erasmus Medical Center - Sophia Children's Hospital, Rotterdam, The Netherlands.;Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands. ^[11]