Phospholipid methylation regulates muscle metabolic rate through Ca<sup>2+</sup> transport efficiency.

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第一作者： Anthony R P,Verkerke

第一单位： Diabetes & Metabolism Research Center, University of Utah, Salt Lake City, UT, USA.

作者： Anthony R P,Verkerke ^[1] ; Patrick J,Ferrara ^[2] ; Chien-Te,Lin ^[1] ; Jordan M,Johnson ^[2] ; Terence E,Ryan ^[3] ; J Alan,Maschek ^[1] ; Hiroaki,Eshima ^[2] ; Christopher W,Paran ^[4] ; Brenton T,Laing ^[5] ; Piyarat,Siripoksup ^[1] ; Trevor S,Tippetts ^[3] ; Edward J,Wentzler ^[3] ; Hu,Huang ^[1] ; Espen E,Spangenburg ^[6] ; Jeffrey J,Brault ^[1] ; Claudio J,Villanueva ^[2] ; Scott A,Summers ^[3] ; William L,Holland ^[3] ; James E,Cox ^[3] ; Dennis E,Vance ^[3] ; P Darrell,Neufer ^[1] ; Katsuhiko,Funai ^[7]

作者单位： Diabetes & Metabolism Research Center, University of Utah, Salt Lake City, UT, USA. ^[1] Department of Nutrition & Integrative Physiology, University of Utah, Salt Lake City, UT, USA. ^[2] East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, NC, USA. ^[3] Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA. ^[4] Metabolomics Core Research Facility, University of Utah, Salt Lake City, UT, USA. ^[5] Department of Physical Therapy & Athletic Training, University of Utah, Salt Lake City, UT, USA. ^[6] Department of Biochemistry, University of Utah, Salt Lake City, UT, USA. ^[7] Molecular Medicine Program, University of Utah, Salt Lake City, UT, USA. ^[8] Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada. ^[9] Diabetes & Metabolism Research Center, University of Utah, Salt Lake City, UT, USA. kfunai@utah.edu. ^[10] Department of Nutrition & Integrative Physiology, University of Utah, Salt Lake City, UT, USA. kfunai@utah.edu. ^[11] East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, NC, USA. kfunai@utah.edu. ^[12] Department of Physical Therapy & Athletic Training, University of Utah, Salt Lake City, UT, USA. kfunai@utah.edu. ^[13] Molecular Medicine Program, University of Utah, Salt Lake City, UT, USA. kfunai@utah.edu. ^[14]

主题词动物(Animals);钙(Calcium);能量代谢(Energy Metabolism);离子转运(Ion Transport);甲基化(Methylation);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);肌, 骨骼(Muscle, Skeletal);肥胖症(Obesity);磷脂酰乙醇胺N-甲基转移酶(Phosphatidylethanolamine N-Methyltransferase);磷脂类(Phospholipids);肌浆网钙转运ATP酶类(Sarcoplasmic Reticulum Calcium-Transporting ATPases)

DOI 10.1038/s42255-019-0111-2

PMID 32405618

发布时间 2021-01-19

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Nature metabolism

2019年1卷9期

876-885页

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Phospholipid methylation regulates muscle metabolic rate through Ca<sup>2+</sup> transport efficiency.

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Phospholipid methylation regulates muscle metabolic rate through Ca<sup>2+</sup> transport efficiency.

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