Overexpression of Fam20C in osteoblast in vivo leads to increased cortical bone formation and osteoclastic bone resorption.

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第一作者： Katsutoshi,Hirose

第一单位： Department of Oral Pathology, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: hirose@dent.osaka-u.ac.jp.

作者： Katsutoshi,Hirose ^[1] ; Takuya,Ishimoto ^[2] ; Yu,Usami ^[3] ; Sunao,Sato ^[4] ; Kaori,Oya ^[5] ; Takayoshi,Nakano ^[6] ; Toshihisa,Komori ^[7] ; Satoru,Toyosawa ^[8]

作者单位： Department of Oral Pathology, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: hirose@dent.osaka-u.ac.jp. ^[1] Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: ishimoto@mat.eng.osaka-u.ac.jp. ^[2] Department of Oral Pathology, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: yusami@dent.osaka-u.ac.jp. ^[3] Department of Oral Pathology, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: sunao@dent.osaka-u.ac.jp. ^[4] Clinical Laboratory, Osaka University Dental Hospital, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: kaori-oya@dent.osaka-u.ac.jp. ^[5] Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: nakano@mat.eng.osaka-u.ac.jp. ^[6] Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8588, Japan. Electronic address: komorit@nagasaki-u.ac.jp. ^[7] Department of Oral Pathology, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan. Electronic address: toyosawa@dent.osaka-u.ac.jp. ^[8]

关键词 Bone formation Bone quality Bone resorption Fam20C Mineralization Osteoblast Phosphorylation Transgenic mice