Trigger-dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis.

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作者： Ruth,Gather ^[1] ; Peter,Aichele ^[2] ; Nadja,Goos ^[3] ; Jan,Rohr ^[1] ; Hanspeter,Pircher ^[1] ; Tamara,Kögl ^[4] ; Robert,Zeiser ^[3] ; Hartmut,Hengel ^[3] ; Annette,Schmitt-Gräff ^[5] ; Casey,Weaver ^[6] ; Stephan,Ehl ^[7]

作者单位： Center for Chronic Immunodeficiency (CCI), Faculty of Medicine, Institute for Immunodeficiency, Medical Center, University of Freiburg, Germany. ^[1] Faculty of Biology, University of Freiburg, Germany. ^[2] Faculty of Medicine, Institute of Immunology, Medical Center, University of Freiburg, Germany. ^[3] Center for Pediatrics and Adolescent Medicine, Faculty of Medicine, Medical Center, University of Freiburg, Germany. ^[4] Department of Hematology and Oncology, Medical Center, University of Freiburg, Germany. ^[5] Faculty of Medicine, Institute of Virology, Medical Center, University of Freiburg, Germany. ^[6] Department of General Pathology, Faculty of Medicine, Institute of Pathology, Medical Center, University of Freiburg, Germany. ^[7] Department of Immunology, School of Medicine, University of Alabama, Birmingham, AL, USA. ^[8]

关键词 hemophagocytic lymphohistiocytosis immunodeficiency immunotherapy lymphocyte cytotoxicity viral infection