Ramipril pretreatment worsened renal injury and survival despite a reduction in renal inflammation in experimentally induced sepsis in mice.

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作者： Tzvetanka,Bondeva ^[1] ; Katrin,Schindler ^[1] ; Claudia,Schindler ^[2] ; Gunter,Wolf ^[1]

作者单位： Department of Internal Medicine III, Jena University Hospital, Germany. ^[1] Institute of Human genetic, Jena University Hospital, Germany. ^[2] Department of Experimental Surgery, Jena University Hospital, Germany. ^[3]

关键词 AKI HIFs Ramipril apoptosis sepsis

主题词急性肾损伤(Acute Kidney Injury);血管紧张素转换酶抑制药(Angiotensin-Converting Enzyme Inhibitors);动物(Animals);细胞凋亡(Apoptosis);碱性螺旋-环-螺旋转录因子类(Basic Helix-Loop-Helix Transcription Factors);基因表达调控(Gene Expression Regulation);炎症(Inflammation);肾(Kidney);肾功能试验(Kidney Function Tests);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);RNA, 信使(RNA, Messenger);雷米普利(Ramipril);肾素(Renin);脓毒症(Sepsis)

DOI 10.1177/1470320320923977

PMID 32419571

发布时间 2022-04-14

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Journal of the renin-angiotensin-aldosterone system

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Ramipril pretreatment worsened renal injury and survival despite a reduction in renal inflammation in experimentally induced sepsis in mice.

Journal of the renin-angiotensin-aldosterone system

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Journal of the renin-angiotensin-aldosterone system

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Ramipril pretreatment worsened renal injury and survival despite a reduction in renal inflammation in experimentally induced sepsis in mice.

Journal of the renin-angiotensin-aldosterone system

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Journal of the renin-angiotensin-aldosterone system

相关期刊

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