首页> Heliyon> The dynamic landscape of <i>BRCA1</i> reversion mutations from indel to SNV in a patient with ovarian cancer treated with PARP-inhibitors and immunotherapy.

The dynamic landscape of <i>BRCA1</i> reversion mutations from indel to SNV in a patient with ovarian cancer treated with PARP-inhibitors and immunotherapy.

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第一作者： Saya L,Jacob

第一单位： Northwestern University Feinberg School of Medicine, Chicago IL, USA.

作者： Saya L,Jacob ^[1] ; Lesli A,Kiedrowski ^[2] ; Young K,Chae ^[3]

作者单位： Northwestern University Feinberg School of Medicine, Chicago IL, USA. ^[1] Guardant Health, Redwood City, CA, USA. ^[2] Northwestern University Feinberg School of Medicine, Chicago IL, USA.;Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA. ^[3]

关键词 Biological sciences Cancer research Clinical research Genetics Molecular biology Molecular genetics Next generation sequencing Oncology Organ system Pathophysiology Pharmaceutical science Proteins Translational science

DOI 10.1016/j.heliyon.2020.e03841

PMID 32420470

发布时间 2022-04-14

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2020年6卷5期

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The dynamic landscape of <i>BRCA1</i> reversion mutations from indel to SNV in a patient with ovarian cancer treated with PARP-inhibitors and immunotherapy.

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The dynamic landscape of <i>BRCA1</i> reversion mutations from indel to SNV in a patient with ovarian cancer treated with PARP-inhibitors and immunotherapy.

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