Seminal Plasma-Derived Extracellular-Vesicle Fractions from HIV-Infected Men Exhibit Unique MicroRNA Signatures and Induce a Proinflammatory Response in Cells Isolated from the Female Reproductive Tract.

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第一作者： Erika G,Marques de Menezes

第一单位： Vitalant Research Institute, San Francisco, California, USA.;Department of Laboratory Medicine, University of California, San Francisco, California, USA.

作者： Erika G,Marques de Menezes ^[1] ; Karen,Jang ^[2] ; Ashley F,George ^[2] ; Mette,Nyegaard ^[3] ; Jason,Neidleman ^[2] ; Heather C,Inglis ^[4] ; Ali,Danesh ^[4] ; Xutao,Deng ^[4] ; Amirali,Afshari ^[5] ; Young H,Kim ^[6] ; Jean-Noël,Billaud ^[7] ; Kara,Marson ^[8] ; Christopher D,Pilcher ^[8] ; Satish K,Pillai ^[1] ; Philip J,Norris ^[9] ; Nadia R,Roan ^[10]

作者单位： Vitalant Research Institute, San Francisco, California, USA.;Department of Laboratory Medicine, University of California, San Francisco, California, USA. ^[1] Gladstone Institute of Virology and Immunology, San Francisco, California, USA.;Department of Urology, University of California, San Francisco, California, USA. ^[2] Department of Biomedicine, Aarhus University, Aarhus, Denmark. ^[3] Vitalant Research Institute, San Francisco, California, USA. ^[4] System Biosciences, Inc., Palo Alto, California, USA. ^[5] Agilent Technologies, Inc., Santa Clara, California, USA. ^[6] Qiagen Bioinformatics, Redwood City, California, USA. ^[7] Division of HIV, Infectious Diseases and Global Medicine, Department of Medicine, University of California, San Francisco, California, USA. ^[8] Vitalant Research Institute, San Francisco, California, USA.;Department of Laboratory Medicine, University of California, San Francisco, California, USA.;Department of Medicine, University of California, San Francisco, California, USA. ^[9] Gladstone Institute of Virology and Immunology, San Francisco, California, USA nadia.roan@ucsf.edu.;Department of Urology, University of California, San Francisco, California, USA. ^[10]

关键词 epithelial cells extracellular vesicles female reproductive tract human immunodeficiency virus miRNAs seminal plasma stromal fibroblasts transcription