Monounsaturated fat rapidly induces hepatic gluconeogenesis and whole-body insulin resistance.

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第一作者： Theresia,Sarabhai

第一单位： Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

作者： Theresia,Sarabhai ^[1] ; Sabine,Kahl ^[2] ; Julia,Szendroedi ^[1] ; Daniel F,Markgraf ^[2] ; Oana-Patricia,Zaharia ^[1] ; Cristina,Barosa ^[2] ; Christian,Herder ^[1] ; Frithjof,Wickrath ^[2] ; Pavel,Bobrov ^[1] ; Jong-Hee,Hwang ^[2] ; John Griffith,Jones ^[3] ; Michael,Roden ^[4]

作者单位： Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany. ^[1] German Center for Diabetes Research, München-Neuherberg, Germany. ^[2] Centre for Neurosciences and Cell Biology, UC Biotech, Cantanhede, Portugal. ^[3] Portuguese Diabetes Association, Lisbon, Portugal. ^[4] Institute for Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany. ^[5] Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany. ^[6]

关键词 Diabetes Endocrinology Glucose metabolism Insulin signaling Metabolism

主题词成年人(Adult);交叉研究(Cross-Over Studies);膳食脂肪类(Dietary Fats);脂肪酸类, 单不饱和(Fatty Acids, Monounsaturated);女(雌)性(Female);糖原异生(Gluconeogenesis);人类(Humans);胰岛素抗药性(Insulin Resistance);肝(Liver);男(雄)性(Male)

DOI 10.1172/jci.insight.134520

PMID 32434996

发布时间 2021-05-18

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2020年5卷10期

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Monounsaturated fat rapidly induces hepatic gluconeogenesis and whole-body insulin resistance.

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Monounsaturated fat rapidly induces hepatic gluconeogenesis and whole-body insulin resistance.

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