Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction.

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作者： Jesus M,Ontoria ^[1] ; Ilaria,Biancofiore ^[1] ; Paola,Fezzardi ^[1] ; Federica,Ferrigno ^[1] ; Esther,Torrente ^[1] ; Stefania,Colarusso ^[1] ; Elisabetta,Bianchi ^[1] ; Matteo,Andreini ^[1] ; Alexandros,Patsilinakos ^[1] ; Georg,Kempf ^[2] ; Martin,Augustin ^[2] ; Stefan,Steinbacher ^[2] ; Vincenzo,Summa ^[1] ; Robert,Pacifici ^[3] ; Ignacio,Muñoz-Sanjuan ^[3] ; Larry,Park ^[3] ; Alberto,Bresciani ^[1] ; Celia,Dominguez ^[3] ; Leticia Toledo,Sherman ^[3] ; Steven,Harper ^[1]

作者单位： IRBM S.p.A., Via Pontina km 30.600, 00071 Pomezia, Rome, Italy. ^[1] Proteros Biostructures GmbH, Bunsenstraße 7 a, 82152 Planegg, Germany. ^[2] CHDI Management/CHDI Foundation, 6080 Center Drive, Los Angeles, California 90045, United States. ^[3]

DOI 10.1021/acsmedchemlett.9b00594

PMID 32435379

发布时间 2021-05-14

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ACS medicinal chemistry letters

2020年11卷5期

740-746页

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Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction.

ACS medicinal chemistry letters

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ACS medicinal chemistry letters

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Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction.

ACS medicinal chemistry letters

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ACS medicinal chemistry letters

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