Metabolomics of a mouse model of preeclampsia induced by overexpressing soluble fms-like tyrosine kinase 1.

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作者： Emiko,Sato ^[1] ; Yukako,Tsunokuni ^[2] ; Manami,Kaneko ^[2] ; Daisuke,Saigusa ^[3] ; Ritsumi,Saito ^[3] ; Shuichi,Shimma ^[4] ; Akiyo,Sekimoto ^[1] ; Yoshiko,Kawana ^[2] ; Yuji,Oe ^[5] ; Sadayoshi,Ito ^[6] ; Hiroshi,Sato ^[1] ; Nobuyuki,Takahashi ^[7]

作者单位： Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, 980-8578, Japan; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan. ^[1] Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, 980-8578, Japan. ^[2] Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8573, Japan. ^[3] Department of Biotechnology, Graduate School of Engineering, Osaka University, Suita, 565-0871, Japan. ^[4] Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan; Division of Feto-Maternal Medical Science, Department of Community Medical Support, Tohoku Medical Megabank Organization, Tohoku University, Sendai, 980-8574, Japan. ^[5] Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan. ^[6] Division of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences, Sendai, 980-8578, Japan; Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan. Electronic address: nobuyuki.takahashi.a8@tohoku.ac.jp. ^[7]

关键词 Acetylcarnitine Carnitine Early-onset PE Metabolomics Nicotinamide Preeclampsia