Identification of benzothiazinones containing 2-benzyl-2,7-diazaspiro[3.5]nonane moieties as new antitubercular agents.

导出 LinkOut

翻译打印收藏纠错

作者： Apeng,Wang ^[1] ; Chao,Ma ^[1] ; Yun,Chai ^[2] ; Xiujun,Liu ^[1] ; Kai,Lv ^[1] ; Lei,Fu ^[3] ; Bin,Wang ^[3] ; Xuedong,Jia ^[4] ; Mingliang,Liu ^[5] ; Yu,Lu ^[6]

作者单位： Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. ^[1] Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China; Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an, Shanxi, 710072, China. ^[2] Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Department of Pharmacology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital College of Pharmacy, Medical University, Beijing, 100149, China. ^[3] The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. ^[4] Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China. Electronic address: lmllyx@126.com. ^[5] Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Department of Pharmacology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital College of Pharmacy, Medical University, Beijing, 100149, China. Electronic address: luyu4876@hotmail.com. ^[6]

关键词 2,7-diazaspiro[3.5]nonane Antimycobacterial activity Benzothiazinones Synthesis