Lgr5-positive endothelial progenitor cells occupy a tumor and injury prone niche in the kidney vasa recta.

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作者： Mike R,Wilson ^[1] ; Jeanne,Holladay ^[1] ; Rachael,Sheridan ^[2] ; Galen,Hostetter ^[3] ; Bree,Berghuis ^[3] ; Carrie,Graveel ^[4] ; Curt,Essenburg ^[4] ; Anderson,Peck ^[5] ; Thai H,Ho ^[6] ; Melissa,Stanton ^[7] ; Ronald L,Chandler ^[8]

作者单位： Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, MI 49503, USA. ^[1] Flow Cytometry Core, Van Andel Research Institute, Grand Rapids, MI 49503, USA. ^[2] Pathology and Biorepository Core, Van Andel Research Institute, Grand Rapids, MI 49503, USA. ^[3] Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503, USA. ^[4] Small Animal Imaging Facility, Van Andel Research Institute, Grand Rapids, MI 49503, USA. ^[5] Division of Hematology and Medical Oncology, Mayo Clinic, Phoenix, AZ 85054, USA. ^[6] Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ 85259, USA. ^[7] Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, MI 49503, USA; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA; Department of Women's Health, Spectrum Health System, Grand Rapids, MI 49341, USA. Electronic address: rlc@msu.edu. ^[8]

关键词 Acute kidney injury Ischemia Stem cells Vasa recta

主题词动物(Animals);毛细血管(Capillaries);肾(Kidney);肾髓质(Kidney Medulla);小鼠(Mice);肿瘤(Neoplasms);受体, G-蛋白偶联(Receptors, G-Protein-Coupled)

DOI 10.1016/j.scr.2020.101849

PMID 32464345

发布时间 2022-05-31

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