换一批Cre/loxP approach-mediated downregulation of Pik3c3 inhibits the hypertrophic growth of renal proximal tubule cells.
第一作者：
Ting,Liu
第一单位：
Departments of Cellular Biology & Anatomy and Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia.
作者：
医学主题词
动物(Animals);III类磷脂酰肌醇3-激酶类(Class III Phosphatidylinositol 3-Kinases);细胞外基质蛋白质类(Extracellular Matrix Proteins);基因表达调控, 发育期(Gene Expression Regulation, Developmental);人类(Humans);整合酶类(Integrases);肾(Kidney);肾小管, 近端(Kidney Tubules, Proximal);小鼠(Mice);肾切除术(Nephrectomy);肾单位(Nephrons);磷酰化(Phosphorylation);蛋白赖氨酸6-氧化酶(Protein-Lysine 6-Oxidase);核糖体蛋白质S6激酶类, 90-kDa(Ribosomal Protein S6 Kinases, 90-kDa);信号传导(Signal Transduction);西罗莫司(Sirolimus);钠-磷协同转运蛋白质类, Ⅱa型(Sodium-Phosphate Cotransporter Proteins, Type IIa)
DOI
10.1002/jcp.29811
PMID
32474911
发布时间
2022-12-07
基金项目
P30 AR074992/AR/NIAMS NIH HHS/United States
R01 DK083575/DK/NIDDK NIH HHS/United States
R01 DK114328/DK/NIDDK NIH HHS/United States
- 浏览2
Journal of cellular physiology
9958-9973页
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