Oral delivery and enhanced efficacy of antimonal drug through macrophage-guided multifunctional nanocargoes against visceral Leishmaniasis.

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第一作者： Hafiz,Shoaib Sarwar

第一单位： Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan; Riphah Institute of Pharmaceutical Sciences (RIPS), Riphah International University, Lahore Campus, Lahore, Pakistan; Department of Pathology, Ohio State University Medical Center, Columbus, OH 43201, United States.

作者： Hafiz,Shoaib Sarwar ^[1] ; Sanjay,Varikuti ^[2] ; Muhammad,Farhan Sohail ^[3] ; Muhammad,Sarwar ^[4] ; Sohail,Akhtar ^[5] ; Abhay R,Satoskar ^[6] ; Gul,Shahnaz ^[7]

作者单位： Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan; Riphah Institute of Pharmaceutical Sciences (RIPS), Riphah International University, Lahore Campus, Lahore, Pakistan; Department of Pathology, Ohio State University Medical Center, Columbus, OH 43201, United States. ^[1] Department of Pathology, Ohio State University Medical Center, Columbus, OH 43201, United States. ^[2] Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan; Riphah Institute of Pharmaceutical Sciences (RIPS), Riphah International University, Lahore Campus, Lahore, Pakistan. ^[3] Department of Statistics, Government Postgraduate College, Sahiwal, Pakistan. ^[4] Department of Entomology, University College of Agriculture & Environmental Sciences, The Islamia University, Bahawalpur, Pakistan. ^[5] Department of Pathology, Ohio State University Medical Center, Columbus, OH 43201, United States. Electronic address: Abhay.Satoskar@osumc.edu. ^[6] Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan. Electronic address: gshahnaz@qau.edu.pk. ^[7]

关键词 Leishmaniasis Macrophage targeting Mannose receptors Meglumine antimoniate Oral delivery