Hepatitis B Virus DNA is a Substrate for the cGAS/STING Pathway but is not Sensed in Infected Hepatocytes.

导出 OA

翻译打印收藏纠错

作者： Lise,Lauterbach-Rivière ^[1] ; Maïwenn,Bergez ^[1] ; Saskia,Mönch ^[1] ; Bingqian,Qu ^[2] ; Maximilian,Riess ^[1] ; Florian W R,Vondran ^[3] ; Juliane,Liese ^[4] ; Veit,Hornung ^[5] ; Stephan,Urban ^[6] ; Renate,König ^[2]

作者单位： Host-Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany. ^[1] Department of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, 69120 Heidelberg, Germany. ^[2] Regenerative Medicine and Experimental Surgery (ReMediES), Department of General, Visceral and Transplant Surgery, Hannover Medical School, 30625 Hannover, Germany. ^[3] German Centre for Infection Research (DZIF), Hannover-Braunschweig, 38124 Braunschweig, Germany. ^[4] Department of General and Thoracic Surgery, Justus-Liebig-University Giessen, 35392 Giessen, Germany. ^[5] Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, 81377 Munich, Germany. ^[6] German Center for Infection Research (DZIF), 69120 Heidelberg, Germany. ^[7] German Center for Infection Research (DZIF), 63225 Langen, Germany. ^[8] Sanford Burnham Prebys Medical Discovery Institute, Immunity and Pathogenesis Program, La Jolla, CA 92037, USA. ^[9]

关键词 STING cGAS hepatitis B virus (HBV)innate immune sensing innate immunity interferon response