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首页> Cellular and molecular neurobiology> Valproate-Induced Epigenetic Upregulation of Hypothalamic Fto Expression Potentially Linked with Weight Gain.

Valproate-Induced Epigenetic Upregulation of Hypothalamic Fto Expression Potentially Linked with Weight Gain.

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作者： Huan,Zhang ^[1] ; Ping,Lu ^[2] ; Hui-Ling,Tang ^[1] ; Hua-Juan,Yan ^[2] ; Wei,Jiang ^[1] ; Hang,Shi ^[2] ; Si-Yu,Chen ^[1] ; Mei-Mei,Gao ^[2] ; Xiang-Da,Zeng ^[1] ; Yue-Sheng,Long ^[2]

作者单位： Institute of Neuroscience and the Second Affiliated Hospital of Guangzhou Medical University, 250 Changang East Road, Guangzhou, 510260, China. ^[1] Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou, 510260, China. ^[2] Institute of Neuroscience and the Second Affiliated Hospital of Guangzhou Medical University, 250 Changang East Road, Guangzhou, 510260, China. longyuesheng@gzhmu.edu.cn. ^[3] Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou, 510260, China. longyuesheng@gzhmu.edu.cn. ^[4]

关键词 Body weight Epigenetic regulation FTO Hypothalamus Valproate

主题词动物(Animals);抗惊厥药(Anticonvulsants);剂量效应关系, 药物(Dose-Response Relationship, Drug);进食(Eating);后成说, 遗传(Epigenesis, Genetic);基因表达(Gene Expression);下丘脑(Hypothalamus);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);增量调节(Up-Regulation);丙戊酸(Valproic Acid);体重增长(Weight Gain)

DOI 10.1007/s10571-020-00895-2

PMID 32500354

发布时间 2024-03-21

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Cellular and molecular neurobiology

Cellular and molecular neurobiology

2021年41卷6期

1257-1269页

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