Proteins and Molecular Pathways Relevant for the Malignant Properties of Tumor-Initiating Pancreatic Cancer Cells.

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第一作者： Lisa,Samonig

第一单位： Department of Biosciences, Bioanalytical Research Labs, University of Salzburg, A-5020 Salzburg, Austria.

作者： Lisa,Samonig ^[1] ; Andrea,Loipetzberger ^[2] ; Constantin,Blöchl ^[1] ; Marc,Rurik ^[3] ; Oliver,Kohlbacher ^[4] ; Fritz,Aberger ^[5] ; Christian G,Huber ^[6]

作者单位： Department of Biosciences, Bioanalytical Research Labs, University of Salzburg, A-5020 Salzburg, Austria. ^[1] Department of Biosciences, Cancer Cluster Salzburg, Molecular Cancer and Stem Cell Research, University of Salzburg, A-5020 Salzburg, Austria. ^[2] Institute for Bioinformatics and Medical Informatics, University of Tübingen, Sand 14, 72076 Tübingen, Germany. ^[3] Institute for Bioinformatics and Medical Informatics, University of Tübingen, Sand 14, 72076 Tübingen, Germany.;Biomolecular Interactions, Max Planck Institute for Developmental Biology, Max-Planck-Ring 5, 72076 Tübingen, Germany.;Institute for Translational Bioinformatics, University Hospital Tübingen, Hoppe-Seyler-Str. 9, 72076 Tübingen, Germany.;Quantitative Biology Center, University of Tübingen, Auf der Morgenstelle 10, 72076 Tübingen, Germany. ^[4] Department of Biosciences, Cancer Cluster Salzburg, Molecular Cancer and Stem Cell Research, University of Salzburg, A-5020 Salzburg, Austria.;Department of Biosciences, Cancer Cluster Salzburg, University of Salzburg, A-5020 Salzburg, Austria. ^[5] Department of Biosciences, Bioanalytical Research Labs, University of Salzburg, A-5020 Salzburg, Austria.;Department of Biosciences, Cancer Cluster Salzburg, University of Salzburg, A-5020 Salzburg, Austria. ^[6]

关键词 CSCs LGALS3BP MAC-2-BP MRP14 MRP8 S100 proteins S100A8 S100A9 TICs cancer stem cells differential proteome analysis functional assays proteomics tumor grafting model

主题词动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);小鼠, 裸(Mice, Nude);肿瘤蛋白质类(Neoplasm Proteins);肿瘤干细胞(Neoplastic Stem Cells);胰腺肿瘤(Pancreatic Neoplasms);主成分分析(Principal Component Analysis);蛋白质组(Proteome);蛋白质组学(Proteomics);RNA, 信使(RNA, Messenger);结果可重复性(Reproducibility of Results);信号传导(Signal Transduction);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.3390/cells9061397

PMID 32503348

发布时间 2024-03-29

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Cells

2020年9卷6期

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