Puerarin ameliorated pressure overload-induced cardiac hypertrophy in ovariectomized rats through activation of the PPARα/PGC-1 pathway.

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作者： Ning,Hou ^[1] ; Yin,Huang ^[2] ; Shao-Ai,Cai ^[1] ; Wen-Chang,Yuan ^[3] ; Li-Rong,Li ^[1] ; Xia-Wen,Liu ^[2] ; Gan-Jian,Zhao ^[1] ; Xiao-Xia,Qiu ^[2] ; Ai-Qun,Li ^[1] ; Chuan-Fang,Cheng ^[2] ; Shi-Ming,Liu ^[1] ; Xiao-Hui,Chen ^[2] ; Dao-Feng,Cai ^[4] ; Jing-Xuan,Xie ^[1] ; Min-Sheng,Chen ^[1] ; Cheng-Feng,Luo ^[1]

作者单位： Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, China. ^[1] Key Laboratory of Molecular Target and Clinical Pharmacology, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, China. ^[2] Xiangtan Central Hospital, Xiangtan, 411100, China. ^[3] Nanfang College of SUN YAT-SEN University, Guangzhou, 510970, China. ^[4] Guangdong Provincial Biomedical Engineering Technology Research Center for Cardiovascular Disease, Sino-Japanese Cooperation Platform for Translational Research in Heart Failure, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China. gzminsheng@vip.163.com. ^[5] Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, China. rocenphone@gzhmu.edu.cn. ^[6]

关键词 PPARα abdominal aortic constriction cardiac hypertrophy ovariectomy puerarin