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首页> Frontiers in immunology> CD4<sup>+</sup> T Cells of Myasthenia Gravis Patients Are Characterized by Increased IL-21, IL-4, and IL-17A Productions and Higher Presence of PD-1 and ICOS.

CD4<sup>+</sup> T Cells of Myasthenia Gravis Patients Are Characterized by Increased IL-21, IL-4, and IL-17A Productions and Higher Presence of PD-1 and ICOS.

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作者： Merve,Çebi ^[1] ; Hacer,Durmus ^[2] ; Fikret,Aysal ^[3] ; Berker,Özkan ^[4] ; Gizem Engin,Gül ^[5] ; Arman,Çakar ^[2] ; Mehmet,Hocaoglu ^[1] ; Metin,Mercan ^[6] ; Sibel P,Yentür ^[1] ; Melih,Tütüncü ^[7] ; Vildan,Yayla ^[6] ; Onur,Akan ^[5] ; Öner,Dogan ^[8] ; Yeşim,Parman ^[2] ; Güher,Saruhan-Direskeneli ^[1]

作者单位： Department of Physiology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. ^[1] Department of Neurology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. ^[2] Department of Neurology, Medipol University, Istanbul, Turkey. ^[3] Department of Thoracic Surgery, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. ^[4] Okmeydani State Hospital, Istanbul, Turkey. ^[5] Bakirköy Sadi Konuk State Hospital, Istanbul, Turkey. ^[6] Department of Neurology, Cerrahpaşa Medical Faculty, Istanbul University Cerrahpaşa, Istanbul, Turkey. ^[7] Department of Pathology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. ^[8]

关键词 CXCR5 ICOS IL-17 IL-21 IL-4 PD-1 T follicular helper cells myasthenia gravis

主题词青少年(Adolescent);成年人(Adult);老年人(Aged);自身抗体(Autoantibodies);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);女(雌)性(Female);人类(Humans);免疫抑制剂(Immunosuppressive Agents);白细胞介素17(Interleukin-17);白细胞介素4(Interleukin-4);白细胞介素类(Interleukins);男(雄)性(Male);中年人(Middle Aged);重症肌无力(Myasthenia Gravis);受体, 胆碱能(Receptors, Cholinergic);信号传导(Signal Transduction);青年人(Young Adult)

DOI 10.3389/fimmu.2020.00809

PMID 32508812

发布时间 2021-12-04

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Frontiers in immunology

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