Exploring the Chemoselectivity towards Cysteine Arylation by Cyclometallated Au<sup>III</sup> Compounds: New Mechanistic Insights.

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第一作者： Sophie R,Thomas

第一单位： School of Chemistry, Cardiff University Main Building, Park Place, CF10 3AT, Cardiff, UK.

作者： Sophie R,Thomas ^[1] ; Riccardo,Bonsignore ^[1] ; Jorge,Sánchez Escudero ^[1] ; Samuel M,Meier-Menches ^[2] ; Christopher M,Brown ^[3] ; Michael O,Wolf ^[3] ; Giampaolo,Barone ^[4] ; Louis Y P,Luk ^[1] ; Angela,Casini ^[5]

作者单位： School of Chemistry, Cardiff University Main Building, Park Place, CF10 3AT, Cardiff, UK. ^[1] Department of Analytical Chemistry Faculty of Chemistry, University of Vienna, Waehringer Str. 38, 1090, Vienna, Austria. ^[2] Department of Chemistry, University of British Columbia, 2036 Main Mall, V6T 1Z1, Vancouver, BC, Canada. ^[3] Dipartimento di Scienze e Tecnologie Biologiche, Chimiche e Farmaceutiche, Università degli Studi di Palermo, Viale delle Scienze, Edificio 17, 90128, Palermo, Italy. ^[4] Department of Chemistry, Technical University of Munich, Lichtenbergstrasse 4, 85747, Garching, Germany. ^[5]

关键词 chemoselectivity cyclometallated gold complexes cysteine arylation mass spectrometry peptides

主题词半胱氨酸(Cysteine);金(Gold);模型, 分子(Models, Molecular);分子结构(Molecular Structure);有机金化合物(Organogold Compounds);肽类(Peptides)

DOI 10.1002/cbic.202000262

PMID 32511840

发布时间 2024-08-04

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