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New approach methodologies (NAMs) for human-relevant biokinetics predictions. Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment

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第一作者: Ans,Punt
第一单位: WFSR Wageningen Food Safety Research, Wageningen, The Netherlands.
作者单位: WFSR Wageningen Food Safety Research, Wageningen, The Netherlands. [1] Division of Toxicology, Wageningen University and Research, Wageningen, The Netherlands. [2] Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands. [3] European Commission Joint Research Centre, Ispra, Italy. [4] RIVM - The National Institute for Public Health and the Environment, Bilthoven, The Netherlands. [5] Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden. [6] Division of Molecular and Computational Toxicology, Dept. Of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. [7] Certara UK Ltd, Simcyp Division, Sheffield, UK. [8] Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands. [9] Shell Health, Shell International B.V., The Hague, The Netherlands. [10] Biomedical Engineering, Cornell University, Department of Biomedical Engineering, Ithaca, NY, USA. [11] Unilever, Colworth Science Park, Bedfordshire, UK. [12] Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, The Netherlands. [13] Van Hall Larenstein University of Applied Sciences, Leeuwarden, The Netherlands. [14] University of Twente, Department of Applied Stem Cell Technologies, Enschede, The Netherlands. [15] Department of In vitro Toxicology and Dermato-Cosmetology, Vrije Universiteit Brussel, Brussels, Belgium. [16] Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research (LACDR)/Leiden University, Leiden, The Netherlands. [17]
DOI 10.14573/altex.2003242
PMID 32521035
发布时间 2021-08-23
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