Chromatin Trapping of Factors Involved in DNA Replication and Repair Underlies Heat-Induced Radio- and Chemosensitization.

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作者： Artem V,Luzhin ^[1] ; Bogdan,Avanesyan ^[2] ; Artem K,Velichko ^[1] ; Victoria O,Shender ^[1] ; Natalia,Ovsyannikova ^[2] ; Georgij P,Arapidi ^[3] ; Polina V,Shnaider ^[4] ; Nadezhda V,Petrova ^[5] ; Igor I,Kireev ^[6] ; Sergey V,Razin ^[4] ; Omar L,Kantidze ^[5]

作者单位： Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia. ^[1] Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia. ^[2] Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, 119991 Moscow, Russia. ^[3] Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia. ^[4] Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia. ^[5] A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia. ^[6] Moscow Institute of Physics and Technology (State University), 141701 Moscow, Russia. ^[7] V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, 117997 Moscow, Russia. ^[8] Department of Biology, Lomonosov Moscow State University, 119992 Moscow, Russia. ^[9]

关键词 DNA repair DNA replication PARP chromatin hyperthermia

主题词染色质(Chromatin);DNA(DNA);DNA损伤(DNA Damage);DNA修复(DNA Repair);DNA复制(DNA Replication);HEK293细胞(HEK293 Cells);热温度(Hot Temperature);人类(Humans);核蛋白质类(Nuclear Proteins);聚腺苷二磷酸酯核糖(Poly Adenosine Diphosphate Ribose);聚ADP核糖聚合酶类(Poly(ADP-ribose) Polymerases)

DOI 10.3390/cells9061423

PMID 32521766

发布时间 2021-03-02

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Cells

2020年9卷6期

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Chromatin Trapping of Factors Involved in DNA Replication and Repair Underlies Heat-Induced Radio- and Chemosensitization.

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Chromatin Trapping of Factors Involved in DNA Replication and Repair Underlies Heat-Induced Radio- and Chemosensitization.

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