Assessment of necroptosis in the retina in a repeated primary ocular blast injury mouse model.

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作者： Chloe N,Thomas ^[1] ; Ella,Courtie ^[2] ; Alexandra,Bernardo-Colón ^[3] ; Gareth,Essex ^[4] ; Tonia S,Rex ^[5] ; Zubair,Ahmed ^[6] ; Richard J,Blanch ^[7]

作者单位： Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; School of Biomedical Sciences, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. ^[1] Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; Ophthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK. ^[2] Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA. ^[3] Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. ^[4] Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine, Nashville, TN, USA. ^[5] Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK. Electronic address: z.ahmed.1@bham.ac.uk. ^[6] Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK; Ophthalmology Department, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK; Academic Department of Military Surgery and Trauma, Royal Centre for Defence Medicine, Birmingham, UK. Electronic address: r.j.blanch@bham.ac.uk. ^[7]

关键词 Cell death Necroptosis Optic nerve Primary blast injury Retina Retinal ganglion cells Traumatic optic neuropathy