Long-term impact of bone-modifying agents for the treatment of bone metastases: a systematic review.

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作者： Terry L,Ng ^[1] ; Megan M,Tu ^[2] ; Mohammed F K,Ibrahim ^[3] ; Bassam,Basulaiman ^[4] ; Sharon F,McGee ^[5] ; Amirrtha,Srikanthan ^[6] ; Ricardo,Fernandes ^[7] ; Lisa,Vandermeer ^[4] ; Carol,Stober ^[8] ; Marta,Sienkiewicz ^[7] ; Ahwon,Jeong ^[4] ; Deanna,Saunders ^[8] ; Arif A,Awan ^[9] ; Brian,Hutton ^[4] ; Mark J,Clemons ^[4]

作者单位： Division of Medical Oncology, Department of Medicine, University of Ottawa, Ottawa, ON, K1H 8L6, Canada. teng@toh.ca. ^[1] Ottawa Hospital Research Institute, Ottawa, ON, Canada. teng@toh.ca. ^[2] Division of Medical Oncology, The Ottawa Hospital Cancer Centre, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada. teng@toh.ca. ^[3] Ottawa Hospital Research Institute, Ottawa, ON, Canada. ^[4] Division of Clinical Sciences, Medical Oncology, Northern Ontario School of Medicine, Thunder Bay, ON, P7B 5E1, Canada. ^[5] Comprehensive Cancer Center -Medical Oncology, King Fahad Medical City, Riyadh, Saudi Arabia. ^[6] Division of Medical Oncology, Department of Medicine, University of Ottawa, Ottawa, ON, K1H 8L6, Canada. ^[7] Division of Medical Oncology, The Ottawa Hospital Cancer Centre, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada. ^[8] Division of Medical Oncology, London Regional Cancer Program, London Health Sciences Centre, University of Western Ontario, London, ON, Canada. ^[9] School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada. ^[10]

关键词 Bisphosphonates Bone metastases Denosumab Skeletal-related events Systematic review