Estrogen induces dynamic ERα and RING1B recruitment to control gene and enhancer activities in luminal breast cancer.

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作者： Yusheng,Zhang ^[1] ; Ho Lam,Chan ^[2] ; Liliana,Garcia-Martinez ^[1] ; Daniel L,Karl ^[2] ; Natalia,Weich ^[1] ; Joyce M,Slingerland ^[2] ; Ramiro E,Verdun ^[1] ; Lluis,Morey ^[1]

作者单位： Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA. ^[1] Department of Human Genetics, University of Miami Miller School of Medicine, Biomedical Research Building, 1501 NW 10th Avenue, Miami, FL 33136, USA. ^[2] Division of Hematology, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA. ^[3] Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA. ^[4] Braman Family Breast Cancer Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA. ^[5]

主题词乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);染色质(Chromatin);雌激素受体α(Estrogen Receptor alpha);雌激素类(Estrogens);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans)

DOI 10.1126/sciadv.aaz7249

PMID 32548262

发布时间 2022-04-08

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Science advances

2020年6卷23期

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Estrogen induces dynamic ERα and RING1B recruitment to control gene and enhancer activities in luminal breast cancer.

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Estrogen induces dynamic ERα and RING1B recruitment to control gene and enhancer activities in luminal breast cancer.

Science advances

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Science advances

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