Delta opioid peptide [d-Ala2, d-Leu5] enkephalin confers neuroprotection by activating delta opioid receptor-AMPK-autophagy axis against global ischemia.

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第一作者： Zelin,Lai

第一单位： Key Laboratory of Brain Functional Genomics (East China Normal University), Ministry of Education, School of Life Sciences, East China Normal University, Shanghai, 200062 China.

作者： Zelin,Lai ^[1] ; Lingling,Gu ^[1] ; Lu,Yu ^[2] ; Huifen,Chen ^[3] ; Zhenhua,Yu ^[1] ; Cheng,Zhang ^[1] ; Xiaoqing,Xu ^[1] ; Mutian,Zhang ^[1] ; Min,Zhang ^[4] ; Mingliang,Ma ^[1] ; Zheng,Zhao ^[5] ; Jun,Zhang ^[1]

作者单位： Key Laboratory of Brain Functional Genomics (East China Normal University), Ministry of Education, School of Life Sciences, East China Normal University, Shanghai, 200062 China. ^[1] Comprehensive Department of Traditional Chinese Medicine, Putuo Hospital, Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, 200062 China. ^[2] Department of Clinical Laboratory, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, 201204 China. ^[3] Department of Clinical Laboratory, Shanghai Public Health Clinical Center, Affiliated to Fudan University, Shanghai, 201508 China. ^[4] Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, 200062 China. ^[5]

关键词 AMPK/mTOR/ULK1 signaling pathway Delta opioid receptor Hippocampus Ischemia/reperfusion injury Neuronal autophagy

DOI 10.1186/s13578-020-00441-z

PMID 32549974

发布时间 2022-04-15

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Cell & bioscience

2020年10卷

79页

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Delta opioid peptide [d-Ala2, d-Leu5] enkephalin confers neuroprotection by activating delta opioid receptor-AMPK-autophagy axis against global ischemia.

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Delta opioid peptide [d-Ala2, d-Leu5] enkephalin confers neuroprotection by activating delta opioid receptor-AMPK-autophagy axis against global ischemia.

Cell & bioscience

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